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Aug 10, 2017 11:34 AM
(294 views)

Hi all,

I plan to run a DOE with three categorical factors. Is Definitive Screening Design is good choice to start with?

Thanks.

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Aug 12, 2017 4:22 AM
(519 views)

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Any screening design depends on the key principles of screening: *sparsity of effects*, *hierarchy of effects*, *heredity of effects*, and *projection of design*. With only three factors, it is unlikely that the first principle will hold. Do you expect that only one of the factors is important?

Also, all screening designs have the attraction of *economy* because some other design methods produce larger designs for the screening case (large number of candidate factors and their associated large number of potential effects). The definitive screening design for three categorical factors includes 14 runs at a minimum and 18 runs with the strongly suggested minimum addition of 4 runs. The size of the DSD is determined by the method, not by you, except for the choice of the number of additional runs. What about the custom design for three categorical factors? Including all three two-factor interactions, the minimum number of runs is 7. A custom design with 12 runs can *estimate all the effects* without fail (even if screening principles do not hold) and *provides high power*: 97% if the effect is at least 3-fold larger than the response standard deviation. (I assume that power for tests of the parameter estimates is important to you because this discussion is about screening.)

An advantage of JMP is that it covers the broad spectrum of situations with the best methods for designing experiments. If you decide that one design method is not the best choice for your situation, then you have the others to fall back on.

Learn it once, use it forever!

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Aug 12, 2017 4:22 AM
(520 views)

Any screening design depends on the key principles of screening: *sparsity of effects*, *hierarchy of effects*, *heredity of effects*, and *projection of design*. With only three factors, it is unlikely that the first principle will hold. Do you expect that only one of the factors is important?

Also, all screening designs have the attraction of *economy* because some other design methods produce larger designs for the screening case (large number of candidate factors and their associated large number of potential effects). The definitive screening design for three categorical factors includes 14 runs at a minimum and 18 runs with the strongly suggested minimum addition of 4 runs. The size of the DSD is determined by the method, not by you, except for the choice of the number of additional runs. What about the custom design for three categorical factors? Including all three two-factor interactions, the minimum number of runs is 7. A custom design with 12 runs can *estimate all the effects* without fail (even if screening principles do not hold) and *provides high power*: 97% if the effect is at least 3-fold larger than the response standard deviation. (I assume that power for tests of the parameter estimates is important to you because this discussion is about screening.)

An advantage of JMP is that it covers the broad spectrum of situations with the best methods for designing experiments. If you decide that one design method is not the best choice for your situation, then you have the others to fall back on.

Learn it once, use it forever!

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