Optimizing Biomanufacturing 1,2,4-butanetriol with JMP Hybrid DOE and SVEM (2026-US-PO-2976)
Biomanufacturing 1,2,4-butanetriol (BT) has been of interest due to its utility as a precursor. Efforts to engineer cells to produce BT have had mixed success. In this project, we explored the production of BT with cell-free metabolic engineering, where cell lysates containing each of the enzymes needed to produce BT are mixed along with the precursor xylose as well as multiple cofactors. The desig...
Skill level:
advanced