topic LD50 and LT50 calculation in Discussions https://community.jmp.com/t5/Discussions/LD50-and-LT50-calculation/m-p/8165#M8159 <HTML><HEAD></HEAD><BODY><P>Hi everybody,</P><P>I would want to calculate LD50 and LT50 from a dataset organized in 6 columns:</P><P>- Name of the compound (I just got 1 compound named A)</P><P>- Concentration of the compound (2 dilutions per compound)</P><P>- Individual number (a fixed number of 10 individuals is used per assay)</P><P>- State of the individual at the end of the experiment (1 = alive, 0 = dead)</P><P>- Day death (experiment last 15 days)</P><P>- Experiment number (2 replicates of the same experiment)</P><P>I drawn kaplan-meyer survival curves (y = day death, censor = state at the end of the experiment). Now I would want to calculate LD50 and LT50 using probit regression but I don't know how to process, could someone help me ?</P><P>Thanks by advance,</P><P>Cécilia</P></BODY></HTML> Wed, 05 Mar 2014 16:13:55 GMT cecilia 2014-03-05T16:13:55Z LD50 and LT50 calculation https://community.jmp.com/t5/Discussions/LD50-and-LT50-calculation/m-p/8165#M8159 <HTML><HEAD></HEAD><BODY><P>Hi everybody,</P><P>I would want to calculate LD50 and LT50 from a dataset organized in 6 columns:</P><P>- Name of the compound (I just got 1 compound named A)</P><P>- Concentration of the compound (2 dilutions per compound)</P><P>- Individual number (a fixed number of 10 individuals is used per assay)</P><P>- State of the individual at the end of the experiment (1 = alive, 0 = dead)</P><P>- Day death (experiment last 15 days)</P><P>- Experiment number (2 replicates of the same experiment)</P><P>I drawn kaplan-meyer survival curves (y = day death, censor = state at the end of the experiment). Now I would want to calculate LD50 and LT50 using probit regression but I don't know how to process, could someone help me ?</P><P>Thanks by advance,</P><P>Cécilia</P></BODY></HTML> Wed, 05 Mar 2014 16:13:55 GMT https://community.jmp.com/t5/Discussions/LD50-and-LT50-calculation/m-p/8165#M8159 cecilia 2014-03-05T16:13:55Z