Defining constrains in a custom design

Reyhanneh — Wed, 11 Dec 2024 13:36:15 GMT

Hi Everyone, I am not sure how to define constraints for my DOE. I have the following factors:

Categorical	Denaturing agent type	Agent 1, Agent 2, Agent 3
Continuous	Denaturing agent concentration	20-100 mM
Categorical	Buffer salt type	Salt 1, Salt 2
Continuous	Buffer salt concentration	10-300
Continuous	X1	8-10
Continuous	X2	0.1-2
Continuous	X3	10-200
Continuous	X4	5-10
Continuous	X5	0.1-2

Per experiment, only one of the denaturing agents {Agent 1, Agent 2, Agent 3} and only one buffer salts {Salt 1, Salt 2} can exist.

How can I define this constraint in JMP? What should I select in the linear or disallowed combination filter?

Thanks

Re: Defining constrains in a custom design

Mark_Bailey — Wed, 11 Dec 2024 14:42:34 GMT

If you define them as categorical factors, only one agent and salt will be included per run.

Reyhanneh — Wed, 11 Dec 2024 16:29:02 GMT

Hi Mark, Thanks for your reply.